Oxiracetam for Memory and Cognitive Abilities

Oxiracetam for Memory and Cognitive Abilities

Have you heard the buzz about how oxiracetam benefits memory and cognitive abilities and what to know more? Or, perhaps you’re trying to compete in a high-pressure job, or simply need help in finding ways to improve your memory.

In this fast-paced, exciting world that is constantly changing, some people have difficulty navigating through the extreme demands of everyday life. However, with clinical studies and documentation of experiences, the oxiracetam effects show increases in mental capabilities including cognition, intelligence, and motivation. Keep reading if you want to learn more about the oxiracetam benefits and how they might fit into your lifestyle.

Why Take Oxiracetam?

Treatments with oxiracetam benefits patients with Alzheimer’s and is in current clinical use in several countries outside the United States. It is also in clinical use for the treatment of the following conditions:

  • Multi-infarct and mixed dementia
  • Memory dysfunction
  • Organic brain syndrome
  • Post-concussion syndrome
  • Traumatic brain injury
  • Organic solvent exposure

Additionally, the positive results from oxiracetam’s off-label uses are also important to report:

  • Better academic performance
  • Enhances cognitive abilities
  • Heightens alertness
  • Promotes logical thinking
  • Increases memory and recall
  • Improves spatial reasoning
  • Acts as an antioxidant in the brain

Student’s experiences show that the use of this supplement increases their motivation to study, and solve complex problems. There are also claims that it gives them better memory retention and recall.

What is Oxiracetam?

Oxiracetam is a synthetic nootropic smart drug. It is a racetam supplement that enhances the mind to bring about clear thinking, better concentration, and sharper focus. The amazing oxiracetam effects also include a greater ability to comprehend and remember information. Moreover, the stimulating effect promotes alertness, but does not interfere with sleep, when taken approximately six hours before bedtime.

The first introduction of oxiracetam was in 1988 in Italy by ICF, an Italian pharmaceutical company. Some countries use it clinically, such as Italy, Malaysia, South Korea, Japan, and China. However, the U.S. FDA has not given approval for this nootropic for the clinical treatment of medical conditions.

Interestingly, you will find this supplement referred to as a smart drug. From a technical viewpoint, smart drugs are supplements that improve memory, and other cognitive functions.

Of course, taking a smart supplement will not give you information that you don’t already have, nor will it magically embed additional knowledge in your brain. Additionally, smart supplements are not a source for getting high.

The point is, they won’t make you smarter or stimulate you to the point of feeling high. But some brain enhancing substances show results of verifiably better health, and cognitive improvement for most people.

You will find the oxiracetam in capsules or powder form. What’s more, it is highly water-soluble for a greater bio-availability. Moreover, oxiracetam is easy to take it with, or without food.

How Does Oxiracetam Work?

As with other racetams, it stimulates the neurotransmitter receptor sites, while it modulates the production and release of acetylcholine and glutamate neurotransmitters. The goal is to keep these particular neurotransmitters at a normal level, for the best memory and focus capabilities.

Additionally, oxiracetam effects include lipid metabolism, while stimulating the release of D-aspartic acid. Both these events improve neural signaling that increases motivation, enhances memory, and improves cognitive ability.

Oxiracetam is also cholinergic which means it responds to, or releases the neurotransmitter acetylcholine, and has the effect of a mild psychostimulant. From this perspective, it is comparable to coffee, although it evokes a lesser degree of stimulation than caffeine.

Nootropic Oxiracetam Benefits

Oxiracetam effects are documented in clinical uses as a nootropic supplement to treat Alzheimer’s disease and other neurological disorders. There is clinical evidence that supports its usefulness in the treatment of dementia. Additionally, it also helps restore memory.

It is best known for its memory enhancing capabilities. Not surprisingly, clinical studies corroborate oxiracetam’s unique memory-boosting qualities. In fact, it is the most widely researched topic about this supplement. However, there are effective off-label uses that are highly sought after because of the oxiracetam benefits.

Some off-label uses are as a nootropic for memory enhancement, increased motivation, along with focus and concentration. This is proven to be especially useful for students when studying, and taking exams.

Oxiracetam  EffectsClinical UseOff-Label Use
Memory ImprovementStudies confirm on both animals and clinical trials on adults with conditions of cognitive decline that it enhances the ability to retain and recall information with a notable increase in speed.Anecdotal evidence by students indicates that it is an incredible memory enhancer.
Learning EnhancementStudies confirm on both animals and clinical trials on adults with dementia that it improves learning.It’s shown to increase capabilities in students for test-taking and logic-intensive subjects.
Concentration and Focus Anecdotal evidence by students improves focus and concentration.
Verbal FluencyStudies confirm that this supplement stems from symptoms of cognitive decline while having a positive effect on verbal fluency in elderly patients with primary or multi-infarct dementia. 
NeuroprotectantAnimal studies suggest that it potentially blocks brain damage from Alzheimer’s disease and other forms of dementia. 
Mild Stimulant Animal studies show that it may inhibit sleep. However, the studies also indicate that it enhances blood flow to the brain which, in turn, improves energy and metabolism.

Negative Effects and Dosage

Always Use the Proper Dosage

The effects of this supplement on your body are contingent on your current medications, your body chemistry, amongst other things. The normal dosage is between 400 – 2,400 mg per day. Going over the recommended dosage limits might cause headaches. The easiest way to avoid this is to lower your dosage.

It’s always best to start any racetam supplement at a low dose, and gradually increase as you feel the need. Here is a guideline for taking oxiracetam.

  • Start at a low daily dose
  • Divide your daily dose over three evenly spread dosing times
  • Avoid taking in the late evening due to its inherent brain-stimulating qualities

Another excellent quality is its unique bio-availability, which means it is easily absorbed after you ingest it. This particular supplement reaches peak levels within 1-3 hours of ingestion. Moreover, it is effective within an hour of taking, and it has a long half-life of 8-10 hours. This quick response time is because of its bio-availability, as it easily crosses over the blood-brain filtering system for faster and better quality results.

Other side effects of over-dosage include; gastrointestinal distress, dizziness, and nausea. Additionally, although it is rare, some people report feelings of nervousness, and sometimes even insomnia.

The good news is, it’s easy to avoid these unpleasant side effects by following the recommended dosage guidelines. You may also simply stop using it for a few days, and then begin taking it again at a lower dose.

Incidentally, there are no cases of injuries or deaths due to the over-dosage of oxiracetam. Neither are there reports of dangerous side effects or incidences.

Stack with Choline to Ease Headaches

Many people report that their headaches (from the use of oxiracetam) disappear when stacking it with choline. Interestingly, many people are choline-deficient, so this might be a good supplement to keep in your daily routine.

Never-the-less, maintaining high enough levels of choline helps eliminate the headaches that are the most common side effect of taking Oxiracetam. Again, the easiest way to decrease headaches is to lower the dosage of oxiracetam.

If you’re looking for a choline supplement, but don’t know where to begin, here is a list of common product names to use in your research.

The most popular choline supplement is Alpha GPC because it has a higher level of bio-availability so that it crosses the blood-brain barrier, and increases acetylcholine production. The others listed are lower in bio-availability and are therefore less effective.

How to Use Before a Learning Event

Evidence shows that students increased their capabilities for test-taking, and solving logic-intensive problems. For the best effects, take the supplement one hour before an exam or learning event.

Additionally, some students report that taking the supplement for at least five days before the event has significant positive effects on their test results.

What Are Racetams?

In general, racetams enhance the brain’s metabolism, and improve communication between the right and left brain hemispheres. Furthermore, you will find them in use in clinical settings with Alzheimer’s patients in addition to aging, non-deteriorated individuals who are simply forgetful. Additionally, as stated before, several reports show positive results for students taking exams.

The most popular racetams are piracetam, aniracetam, and oxiracetam. Oxiracetam (a derivative of piracetam) is similar in its potency, and how it works, to both piracetam and aniracetam. However, there are additional oxiracetam benefits, including; increasing D-aspartic acid, acetylcholine, and glutamate. This addition increases metabolic activity, which enhances memory.

More specifically, piracetam, aniracetam, and oxiracetam all have similar but slightly different benefits. Each have strong nootropic effects, but there are also differences in the effects.

For example, the use of oxiracetam produces similar effects as the other members of the racetam family, but are 3-5 times more potent than piracetam.

Oxiracetam Stack Options

Although oxiracetam works exceptionally well on its own, it also works when stacking with other racetam supplements. However, you must keep in mind that when you combine racetams, it often amplifies effects, so do your research first to ensure the right combination for you, then stack and enjoy the benefits. Here are three suggestions for the most common oxiracetam stacking options.

Choline with Oxiracetam Stack

As mentioned above, some people report headaches when using oxiracetam by itself. The most common way to alleviate this symptom is to stack it with choline. Because the body tends to require more choline when taking racetams, it might be good advice to add it to your daily regimen.

1x – 2x per day

  • 750 mg Oxiracetam supplement
  • 300 mg Choline supplement

Aniracetam with Oxiracetam Stack

Interestingly, oxiracetam does not affect serotonin and dopamine neurotransmitters, so you do not get mood-enhancing effects from this supplement.

But you may use it in combination with aniracetam’s inherent mood-elevating and anxiety-lowering qualities for a distinctively pleasant experience.

1x – 2x per day

  • 750 mg Oxiracetam
  • 750 mg Aniracetam

Pramiracetam with Oxiracetam Stack

When stacked together, these supplements give even greater results for powerful enhancements to memory and cognitive functions.

1x – 2x per day

  • 750 mg Oxiracetam
  • 750 mg Pramiracetam

Tip o’ the hat to Braintropic

Pramiracetam, Aniracetam, and Oxiracetam Comparison

If you’re going to stack these supplements, it’s advisable to do your own research in depth to better understand the oxiracetam effects in comparison to pramiracetam, and aniracetam. Here is a brief overview and comparison of piracetam, oxiracetam, and aniracetam.


  • Short half life
  • Enters the blood quickly
  • Enhances memory and cognition
  • Well-researched
  • Not highly potent
  • Requires higher doses in some people
  • Stimulation at high doses
  • Stacks with choline to improve stimulation
  • Stacks well with other racetams


  • Long half life
  • Enters the blood quickly
  • Enhances memory and cognition
  • Increases attention and focus
  • Well-researched
  • Derivative of piracetam
  • Significantly more potent than piracetam
  • May require choline stack for headaches
  • Stacks well with other racetams


  • Short half life
  • Enters the blood quickly
  • Enhances memory and cognition
  • Elevates mood and feelings of well-being
  • Well-researched
  • Stacks with piracetam to enhance memory and learning
  • Stacks well with other racetams

Here’s to Your Excellent Results

In conclusion, oxiracetam is a synthetic, nootropic supplement from the racetams family. Decades of research show proven results of increased cognitive functioning. Furthermore, clinical trial results show enhancements in memory and recall, a notable increase in learning capabilities, and an improvement in verbal fluency.

Additionally, the oxiracetam benefits include the qualities of a mild stimulant which helps keep you alert. It even has neuroprotective elements that help keep your brain healthy.

It is in clinical use for Alzheimer patients, and other brain disorders, in some countries outside the United States, but, it doesn’t have FDA approval for clinical use. However, you may purchase it from supplement retailers in capsule, or powder form.

Oxiracetam has a strong following among students for its inherent abilities to enhance study skills and test-taking.

Finally, oxiracetam is safe and non-toxic, with no harmful side effects. So, if you want a better memory, more motivation, or just an extra edge over the competition, consider the oxiracetam benefits, and how they might improve your life.

These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.