Coluracetam; a New and Highly Beneficial Nootropic Racetam

Coluracetam; a New and Highly Beneficial Nootropic Racetam

One of the most popular categories of nootropics today is a powerful assortment of brain-boosters called racetams. There are many different racetams and all of them affect your brain in different ways. Recently on this blog, we broke down all the benefits and usage of phenylpiracetam, and today we’ll be looking at coluracetam, which is an equally popular variety. But before we any further, let’s take a quick look at the racetam family and get some background on them as nootropics.

The Role of Racetams

Racetams are a category of nootropics and within that category, they are individually identified with similar structures chemically. The beauty of racetams is that they work to increase the nutrients that your body retains and increases the blood flow. This is in addition to their well-known ability to increase cognitive abilities for better focus and retention.

What is Coluracetam?

Coluracetam is a newer member of the racetam family of nootropics.  It was initially created in 2005 as a possible treatment for Alzheimer’s disease.  Later on, it was looked at as a potential treatment for anxiety and depression. Although it is one of the least known racetams, it has been gaining popularity for its ability to improve mood, motivation, and even boost vision.

Coluracetam’s primary function is to enhance the choline uptake that affects memory function. Most believe that action is the source of Coluracetam’s effectiveness as a nootropic because of the neurotransmitter acetylcholine which identifies most closely with cognition and memory.

Due to its potency, most experts suggest smaller doses of coluracetam as compared to other racetams. Furthermore, the effects of Coluracetam may be felt in as little as 30 minutes after ingestion.

How Coluracetam Works

Coluracetam boosts the levels of the neurotransmitter acetylcholine, which connects to cognition, learning, and memory. Conversely, most other racetams work by prompting acetylcholine production by stimulating the appropriate receptors. However, coluracetam affects acetylcholine in a unique way by boosting high-affinity choline uptake (HACU). Moreover, the HACU system regulates the rate at which choline is absorbed into neurons for transforming into acetylcholine. Because of this, you get a much more potent boost in neurotransmitter levels.

Coluracetam also creates an increase in the choline molecule, which helps make choline more rapidly available. This combination of actions results in higher levels of acetylcholine, which increases better memory cognition.

Coluracetam Brain Boosting Benefits

Coluracetam Benefits

Learning and Memory

Coluracetam users have noted a significant increase in their abilities to memorize and recall information, along with their reading comprehension. Others say that it effectively boosts short-term memory and free recall.

Anxiety and Depression

Although there are very few studies done on human subjects, a 6-week placebo-controlled study shows a total daily dosage of 240mg may be beneficial with those suffering from GAD (generalized anxiety disorder)  or MDD (major depressive disorder).

Once the trial was completed, there was a significant improvement in the group of participants who had both GAD and MDD and who had otherwise failed while using an average of 2 antidepressants.

It should be noted that there is a wide range of noted reactions to Coluracetam when it comes to depression and anxiety. Some report that it lessens both, while others note that it actually brings about both.


Some users of Coluracetam have reported improvements with colors, shapes, and vividness of their eyesight. Others characterize the effect of having “HD Vision”. Although there is no confirmed scientific evidence of enhanced vision, the anecdotal reporting of users claiming Coluracetam improves their eyesight is hard to ignore.

Coluracetam Side Effects

Generally speaking, Coluracetam is safe, non-toxic and well-tolerated by the body. Some first-time users have noted fatigue, which is due in part to a higher minimum dosage. Other side effects that have been reported include nausea, headaches, anxiety, and nervousness. 

As with most racetams, headaches can result when not enough choline is present in the brain.  Therefore, Coluracetam should be taken with a choline supplement or as part of a nootropic stack.

Coluracetam Dosage

Currently, there are no set dosage guidelines for Coluracetam. However, the general dosage range can be a daily total of 20 – 80mg. As with most nootropics, you may want to start off with the lower daily dosage to see how you may react to taking Coluracetam.

For better and faster absorption, some users take Coluracetam sublingually (under the tongue).  It is also fat-soluble, so it should be taken with a meal that includes healthy fats.  It may also be taken with a tablespoon of coconut oil.

Coluracetam is available in powder form, but it may be purchased in liquid form as well.  Coluracetam is not legally sold by prescription in the United States, however, it may be imported and possessed legally.

Coluracetam Stacking

For added cognitive and memory benefits, Coluracetam should always be stacked with a choline source. The recommended dosage for supplemental choline is 300-600 mg a day if you’re stacking with alpha GPC.  If you are using CDP choline, the recommended dosage is 250-750 mg a day.


One of the newer members of the racetam family of nootropics, coluracetam, is quickly gaining popularity for its abilities to improve mood, motivation, memory, and vision.

As more studies are conducted with coluracetam, it is believed it could be a potential treatment for depression and anxiety, and some Coluracetam users note that it enhances mood and boosts memory while giving them better focus and concentration.  Others say that their vision becomes better by making colors brother, lights more radiant, and contrast more intense.

Since it is one of the newer members of the racetam family, there is much still to learn and understand, but when you take coluracetam responsibly, it is generally safe and extremely effective!

These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.