Centrophenoxine Health Benefits & Effects

Centrophenoxine Health Benefits & Effects

What is Centrophenoxine?

Centrophenoxine is one of the original drugs that work against aging. In fact, in animal studies, it shows reductions of lipofuscin levels, but more about that later. Additionally, Europeans use it for brain energy. It also acts as a cholinergic that promotes DMAE absorption. Interestingly, it is an over-the-counter supplement that is in use by many for the prevention and treatment of Alzheimer’s disease.

With over five decades of use and a wide array of studies proving its effectiveness, it is a widely used and well-respected nootropic. Historically, it was developed by scientists in 1959 at the French National Scientific Research Center expressly as a treatment for age-related cognitive decline, Alzheimer’s disease, and low blood flow to the brain.

This popular nootropic is both an effective anti-aging agent, and an incredible memory-booster. In fact, in Europe, you must get a prescription to use it. However, in the US and Canada, it is available in an over-the-counter supplemental form. It is worth noting for your research that centrophenoxine is for sale online and over-the-counter from your local health store under the names of Lucidril or meclofenoxate.

How Does Centrophenoxine Work?

Centrophenoxine classifies as a cholinergic which simply stated means it helps deliver the action of choline. This is significant because choline helps with cognitive function. Therefore, on its own, centrophenoxine is an effective nootropic. However, it can be even more effective in combination with other nootropics. You will find a section on stacking options later in this article.

Even more incredibly, it also shows in some studies to be an effective antioxidant and neuroprotectant.

To explain further about this supplement, let’s explore what is in centrophenoxine and learn some interesting facts about the effects. First, it is a combination of a synthetic version of DMAE (dimethylaminoethanol) and PCPA (para-chlorphenoxyacetic) Next, it is also a fat-soluble compound that the liver easily metabolizes.

Although there are decades of research around this topic, scientists do not yet fully understand the mechanisms of action. However, once it crosses the blood-brain barrier, it either converts into an intermediary phospholipid that then makes acetylcholine or, it breaks down into choline that then converts to acetylcholine.

The primary reason centrophenoxine is such an excellent nootropic is that it increases acetylcholine levels to enhance cognitive abilities. In addition, it also enhances cognition by increases in oxygen and glucose to the brain along with decreases in cellular toxins that deter cognitive abilities.

But that’s not all. It also is an incredible anti-aging supplement because it is an antioxidant that flushes toxins to repair damage to cells. Additionally, centrophenoxine shows in studies to reduce and sometimes eliminate the buildup of lipofuscin. Lipofuscin is a waste that builds up in aging cells and is usually in the cells of the heart muscle, kidney, liver, retina, and in nerve and ganglion cells. Because of its incredible ability to eliminate this buildup, centrophenoxine is a valuable anti-aging tool to consider for your supplement arsenal.

Centrophenoxine Health Benefits & Effects

Centrophenoxine for Focus

Anti-aging and Neuroprotective Qualities

In studies with rats, results show that centrophenoxine increases the lifespan of rats by up to 50%.

Research also suggests that centrophenoxine is both a highly effective antioxidant and a free radical scavenger. This helps protect the brain from age deterioration, gets rid of toxins, and repairs damage to cells.

Of particular note is the ability to reduce the accumulation of lipofuscin from neurons and other cells. Because lipofuscin is strongly related to age-related disorders, many people consider centrophenoxine as their supplement of choice for aging disorders, including Alzheimer’s disease.

Tip o’ the Hat to BRAINTROPIC

Dementia & Centrophenoxine

Centrophenoxine shows in one study to effective in the treatment of dementia. It works by increasing intracellular water content which is helpful because dehydration is one of the signs of aging.

Memory & Learning Enhancements

Again, centrophenoxine shows in studies to be an enhancer of cognitive abilities. In fact, in one study of healthy elderly people, centrophenoxine increases focus and improves long-term memory.

An animal study with mice suggests centrophenoxine increases learning abilities.

Additionally, another study shows that centrophenoxine increases synaptic plasticity which in turn increases fluid intelligence. In other words, it enhances the ability to solve problems without prior knowledge of the topic.

Mood & Motivation Enhancements

Interestingly, centrophenoxine also has an anti-anxiety effect. In addition, some people report a positive effect on both their mood and motivation, like taking a mild anti-depressant.

Centrophenoxine Dosage

For healthy adults, recommendations for supplements start with 250mg taken twice 1 – 3 times daily. For centrophenoxine powder, and for the best results, use 250mg. dosages.

You may take it in one dose or split it up into early morning and early afternoon. You must avoid taking to close to bedtime to avoid sleeplessness simply because this supplement makes you more alert.

For elderly adults seeking the nootropic benefits, start with 3 – 6 daily doses of 250mg. spread out over the day. Again, avoid taking close to bedtime to avoid sleeplessness.

As with all nootropics, start with a low dose and gradually increase on a weekly basis. This will enable you to see how your personal body chemistry reacts when taking the supplement. Then, before taking higher doses, first consult with your doctor.

It is also worth noting that centrophenoxine is fat-soluble, so it is best to take it with food.

Expectations of Centrophenoxine Doses

Cognitive decline in aging people correlates with excess potassium in the brain. Centrophenoxine reduces the amount of potassium in addition to producing proteins and other chemicals that benefit cognitive abilities.

In addition, it is a highly effective antioxidant that helps eliminate free radicals thereby preventing diseases that leads to damage to cells. This action also works to remove harmful toxins from the brain which in turn allows improvements to cognitive functions.

Finally, centrophenoxine abilities include removal of elements that cause cell damage which in effect, gives users assistance against the detrimental actions of diseases and aging.

Centrophenoxine Long-Term Use

Low-dosage, long-term use of centrophenoxine is advisable for keeping potassium levels down which is the culprit for the neuron aging process. Also, the lipofuscin build-up minimizes in the brain and heart which can result in longer life and improvements to mental health.

Centrophenoxine Short-Term Use

Short-term use is advantageous for improvements to memory and learning capabilities. It also helps with brain fog for students and those who need the highest cognitive abilities possible. This is in addition to the increases energy levels that centrophenoxine delivers which also has a positive result for personal motivation.

It is also effective in the reversal of aging when taken in higher dosages for one month. Tip o’ the Hat to Examine.

Centrophenoxine Precautions & Possible Side Effects

Overall, centrophenoxine is non-toxic and safe when taken within the recommended guidelines.

However, there are reports of mild side effects that include headache, gastrointestinal discomfort, nausea, and sleeplessness.

At the same time, studies show that most side effects are easily eliminated by reducing the dosage.

If you are pregnant or lactating, you must refrain from the use of centrophenoxine because it is a derivative of DMAE which may result in teratogenic effects that cause birth defects.

If you are suffering from major depression or seizure disorders, you must refrain from taking centrophenoxine due to possible adverse side effects.

Centrophenoxine Stacking Options

Stacking Recipes Using Centrophenoxine

Aniracetam & Centrophenoxine Stacking Recipe

  • Centrophenoxine 250mg.
  • Aniracetam 750mg.

Noopept & Centrophenoxine Stacking Recipe

  • Centrophenoxine 250mg.
  • Noopept 20mg.

Centrophenoxine & Piracetam Stacking Recipe

  • Stacking ratio 5:1 for up to 1500mg. Centrophenoxine

Other Possible Combinations

Centrophenoxine & Racetams in General

If you seek cholinergic effects, racetam is an important category for you. The racetam includes but is not limited to the following cognitive boosting supplements:

  • Aniracetam
  • Coluracetam
  • Fasoracetam
  • Oxiracetam
  • Phenylpiracetam
  • Piracetam.

However, please note that each racetam works in unique ways with centrophenoxine. That makes it important to be aware that the addition of racetams amplifies the effects of centrophenoxine. Therefore, start with small doses and work up to larger doses if you find it necessary.

Centrophenoxine & Huperzine A

Using huperzine A which is a cholinergic compound is sometimes useful to some people. The recommendation is to start with low doses and increase gradually if necessary.

Centrophenoxine & Modafinil

As we already know, centrophenoxine is a great cognitive enhancer with neuroprotective abilities. When you combine it with modafinil, it increases the abilities of focus and concentration. In fact, in the nootropic’s community, modafinil is a favorite of many.

Prominent Studies for Centrophenoxine

Dementia Patients & Centrophenoxine

This study reports on the effects of treating dementia with centrophenoxine. This was a double-blind trial with 50 men and women who have middle-stage dementia. The results show an increase in cognitive performance and an increase in intracellular water content.

Aging Mice & Centrophenoxine

Another study used old mice to evaluate the effects of centrophenoxine for improvements to cognitive abilities. The results of this study show that the rats given the centrophenoxine supplement can learn tasks faster than mice who did not take the supplement.

Anxiety and Centrophenoxine

In a study in which rats were induced with anxiety, results show a decrease in the symptoms of anxiety when the rats were given either adafenoxate or centrophenoxine.

Parkinson’s Disease and Centrophenoxine

Parkinson’s disease includes a decrease in dopamine’s which brings on the difficulty of movements in the human body. It also includes a decrease in glutathione which is an antioxidant.

In 2009, a study was conducted on rats who were infused with rotenone to initiate the features of Parkinson’s. When given centrophenoxine, the results show a significant decrease in the depletion of dopamine and glutathione. It also resulted in decreases in elevations of nitric oxide which is also a symptom of this disease.

Centrophenoxine Synopsis

With over five decades of use and a wide array of studies, centrophenoxine is proving its effectiveness and is widely in use as a well-respected nootropic.

Centrophenoxine is one of the original drugs that work against aging. In fact, this popular nootropic is both an effective anti-aging agent, and an incredible memory-booster. That’s because it is an anti-aging supplement that flushes toxins to repair damage to cells.

Centrophenoxine also classifies as a cholinergic that helps deliver the action of choline which is significant because choline helps with cognitive function.

However, the primary reason centrophenoxine is such a popular nootropic is that it increases acetylcholine levels to enhance cognitive abilities. Also, cognitive decline in aging people correlates with excess potassium in the brain. Centrophenoxine reduces the amount of potassium in addition to producing proteins and other chemicals that benefit cognitive abilities.

Lipofuscin is a waste substance that builds up in aging cells and is usually in the cells of the heart muscle, kidney, liver, retina, and in nerve and ganglion cells. Because of its incredible ability to eliminate this buildup, centrophenoxine is a valuable anti-aging tool to add to your supplement tool belt.

For healthy adults, recommendations for supplements start with 250mg taken twice 1 – 3 times daily. For centrophenoxine powder, and for the best results, use 250mg. dosages.

As with all nootropics, start with a low dose and gradually increase on a weekly basis. This will enable you to see how your personal body chemistry reacts when taking the supplement. However, it is not advisable to take higher doses without first consulting with your doctor. It is also worth noting that centrophenoxine is fat-soluble, so it is best to take it with food.

These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.

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